Tempol ameliorates polycystic ovary syndrome through attenuating intestinal oxidative stress and modulating of gut microbiota composition-serum metabolites interaction

Li T, Zhang T, Gao H, Liu R, Gu M, Yang Y, Cui T, Lu Z, Yin C.
Redox Biol. 2021 Feb 3;41:101886. doi: 10.1016/j.redox.2021.101886. Online ahead of print. PMID: 33592539 Free article.
Moreover, stachyose administration improved ovarian dysfunction in PCOS rats. Thus, our data indicate that tempol ameliorates PCOS phenotype by reducing intestinal oxidative stress, restoring gut dysbiosis, and modulating the interaction between gut microbiota and h