Regulation of host physiology and immunity by microbial indole-3-aldehyde

Zelante T, Puccetti M, Giovagnoli S, Romani L.
Curr Opin Immunol. 2021 Jan 14;70:27-32. doi: 10.1016/j.coi.2020.12.004. Online ahead of print. PMID: 33454521 Review.
Tryptophan derivatives of host and microbial origin are emblematic of this metabolic promiscuity. …In this review, we describe the multifaceted role of 3-IAld in host physiology, pathology and immunity and discuss how its proper clinical development may tur …