Recombinant antimicrobial peptide microcin J25 alleviates DSS-induced colitis via regulating intestinal barrier function and modifying gut microbiota

Shang L, Yu H, Liu H, Chen M, Zeng X, Qiao S.
Biomed Pharmacother. 2021 Apr 2;139:111127. doi: 10.1016/j.biopha.2020.111127. Online ahead of print. PMID: 33819810
However, current medical treatments are not universally practical. Microcin J25 (MccJ25), a member of the lasso peptides class, has excellent antimicrobial activity both in vitro and in vivo. …