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Monday 5th November 2018, 13.30-18.30
Afternoon Session

10.00 – 13.00 Registration

13.00 – 13.20 Francesco Peri , Opening and welcome address, introduction to MicrobiotaMi 2018

Plenary Session 1
Microbiota/host interaction (innate sensing, gut-brain axis, inflammaging)

Chairman: Roman Jerala

13.20 – 14.20 Judith Campisi (Buck Institute, CA USA)
Senescent cells as drivers of inflammaging

14.20 / OC1 – Esposti Federico (University Vita-Salute San Raffaele, Milan, Italy)
“How the brain responds to bacterial molecules in the gut”
14.35 / OC2 – Rossini Valerio (APC Microbiome Ireland, University College Cork, Ireland)
“Systemic Dissemination of Commensal Bacteria is CX3CR1-dependent and is Mediated by CD11c+ CD103+ Dendritic Cells”
14.50 / OC3 – Gorlé Nina (VIB Center for Inflammation Research, Ghent, Belgium)
“The choroid plexus epithelium as a novel player in the gut-brain axis”

15.05 / Posters Flash Presentations: Merlini E.; Consonni A.; Hafner-Bratkovič I.; Hsu E.; Petra S.; Boscaini S.; Riva A.

15.30 – 16.00 Coffee break & Poster Session

Chairman: Antonio Molinaro

16.00 – 17.00 Duccio Cavalieri (Department of Biology, University of Firenze, Italy)
“Evolutionary Metagenomics: How Globalization and climate change affect microbiomes“

17.00 / OC4 – Hickey Ana (APC Microbiome Ireland, University College Cork, Ireland)
“The Role of Exopolysaccharide in Modulating Host Immune Responses towards Bifidobacterium breve”
17.15 / OC5 – Perruzza Lisa (Institute for Research in Biomedicine, USI, Bellinzona, Switzerland)
“ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens”
17.30 / OC6 – Bosman Else (University of British Columbia)
“UVB light promotes intestinal homeostasis through Ahr activation”

17.45 / Posters Flash Presentations: Zeaiter Z.; Manček-Keber M.; Rossi M.; Soccio P.; Masetti G.; Farini A.; Zafeiropoulou K.; Pellicciota M.; Pinto D.; Pazienza V.

18.30 Welcome cocktail

Tuesday 6th November 2018, 9.00 – 13.00
Morning Session

Plenary Session 2
Microbiota and diseases: inflammation, neurodegeneration, autoimmunity

Chairman: Ivan Zanoni

09.00 – 10.00 Scott Snapper (Harvard, USA)
Immunological and Microbial Mechanisms of Immune Tolerance in the Human Intestine: Insights from Rare Diseases.”

10.00 – 10.30 Nissan Yissachar (Bar-Ilan University Ramat-Gan, Israel)
Thinking outside the mouse: ex-vivo dissections of enteric neuro-immune-microbiome cross talks.”

10.30 / OC07 – Carlo Selmi (University of Milano and Humanitas Research Hospital)
“The role of gender in the connection between the microbiome and autoimmunity.”

10.45 / Posters Flash Presentations: Agostinetto G.; Taverniti V.; Zerkani H.; Pallach M.; Di Lorenzo F.

11.00 – 11:30 Coffee break & Poster Session

Chairman: Ivan Monteleone

11.30 – 12.30 Gabriel Nunez (Department of Pathology Michigan Medicine University of Michigan)
Role of the Microbiota in Health and Inflammatory Disease”.

12.30 / OC8 – Dumas Alexia (IPBS, CNRS)
“The host microbiota contributes to early protection against lung colonization by Mycobacterium tuberculosis”
12.45 / OC9 – Strati Francesco (Institute for Research in Biomedicine, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland)
“Defective purinergic control of T follicular helper cells alters the IgA-targeted gut microbiota and host metabolism”

13.00 – 14.00 Lunch

Tuesday 6th November 2018, 14.00 – 18.15
Afternoon Session

Plenary Session 2
Microbiota and diseases: inflammation, neurodegeneration, autoimmunity

Chairman: Koichi Fukase

14.00 – 15.00 Hiroshi Kiyono (University of Tokyo, Japan)
Mucosal Multi-Ecological Loop of Intra- and Extra-Tissue Commensal Microbiota, Epithelial Cells and Immune Cells for Gut Homeostasis and Inflammation

15.00 / OC10 – Carmen Giordano (Politecnico di Milano, Italy)
MINERVA ERC project: a bioengineered platform for frontier research on microbiota-gut-brain axis
15.15 / OC11 – Pasquale Striano (Gaslini Institute and University of Genova, Italy)
“The bidirectional link between CNS and gut microbiota in epilepsy and other neuropsychiatric disease”
15.30 / OC12 – Holgado Aurora (Inflammation Research Center (IRC)-VIB. Gent, Belgium)
“Effect of IL-33 targeting in fungal microbiota-induced asthma”

15.45 / Posters Flash Presentations: Celine Toe L.; Campisciano G.; Airoldi C.; Pirianov G.

16.00 – 16.30 Coffee break & Poster Session

Chairman: Koichi Fukase

16.30 – 17.30 Jin-ichi Inokuchi (Tohoku Medical and Pharmaceutical University, Japan)
New Paradigm for Chronic Inflammation Mediated by Glycosphingolipids

17.30 / OC 13 – Annamaria Bevivino (ENEA, Roma)
The airway microbiome in cystic fibrosis: where are we now?
17.45 / OC14 – Shimoyama Atsushy (Osaka University)
“Synthesis and functions of symbiotic bacterial lipopolysaccharide partial structures”
18.00 / OC15 – Bernard-Raihcon Lucie (IPBS-CNRS, Toulouse, France) “Identification and characterization of commensal bacteria that grant protection against immunopathology in tuberculosis“

Social event: guided tour to the Museo della Scienza e della Tecnica

Wednesday 7th November 2018, 09.00 – 13.00
Morning Session

Plenary Session 3
Microbiota in nutrition and health

Chairman: Rudi Beyaert

9.00 – 10.00 Maria Rescigno (Humanitas University, Milano, Italy)
Host-microbe interactions in the gut-liver axis

10.00 / OC16 – Hellas Cena (University of Pavia)
Personalized nutrition and human microbiome for NCD prevention and treatment
10.15 / OC17 – Federica Laudisi (Department of System Medicine, University of Rome Tor Vergata, Rome, Italy)
“The food additive maltodextrin promotes endoplasmic reticulum stress-driven mucus depletion and exacerbates intestinal inflammation”
10.30 / OC18 – Burrello Claudia (Department of Oncology and Hemato-oncology, Università degli Studi di Milano, Milan, Italy)
“Antibiotic treatment induces recruitment and inflammatory activation of colonic iNKT cells” 
10.45 / OC19 Annalisa Chioccheti (Department of Health Science and IRCAD and CAAD, University of Piemonte Orientale (UPO), Novara)
“Development and characterization of a new probiotic formulation, EndolaCoa®, in allergic patients”

11.00 – 11.30 Coffee break

11.30 – 12.30 Jerry M. Wells (Department of Animal Sciences, Wageningen University, The Netherlands)
What matters most the microbes or their metabolites?

12.30 / OC20 Giorgia Mori (IEO Milano and University of Pavia)
“Puzzling out gut microbiota composition in sporadic and hereditary colorectal cancer”

12.45 – Closing Remarks