Post-translational suppression of the high affinity IgE receptor expression on mast cells by an intestinal bacterium
Immunobiology. 2021 Jan 23;226(2):152056. doi: 10.1016/j.imbio.2021.152056. Online ahead of print. PMID: 33535092
The suppressive effect required sustained exposure to this bacterium, with a corresponding reduction in Erk activation. Inhibition of Erk decreased cell surface distribution of FcepsilonRI in BMMCs, at least in part, through facilitated endocytosis of FcepsilonRI. These re …
