Microbiome meta-analysis and cross-disease comparison enabled by the SIAMCAT machine learning toolbox

Wirbel J, Zych K, Essex M, Karcher N, Kartal E, Salazar G, Bork P, Sunagawa S, Zeller G.
Genome Biol. 2021 Mar 30;22(1):93. doi: 10.1186/s13059-021-02306-1. PMID: 33785070 Free PMC article.
The human microbiome is increasingly mined for diagnostic and therapeutic biomarkers using machine learning (ML). …We demonstrate its capabilities in a metaanalysis of fecal metagenomic studies (10,803 samples). When naively transferred across studies, ML …