Microbial memories

Wong AC, Levy M.

Immunity. 2021 Feb 9;54(2):201-204. doi: 10.1016/j.immuni.2021.01.009.

The microbiota impedes pathogen invasion of the intestinal ecosystem, a phenomenon termed colonization resistance. In an upcoming issue of Cell, Stacy et al. describe host-initiated metabolite pathways that functionally alter the microbiota after primary infection, thereby augmenting colonization resistance to subsequent infection…