Infection trains the host for microbiota-enhanced resistance to pathogens

Stacy A, Andrade-Oliveira V, McCulloch JA, Hild B, Oh JH, Perez-Chaparro PJ, Sim CK, Lim AI, Link VM, Enamorado M, Trinchieri G, Segre JA, Rehermann B, Belkaid Y.
Cell. 2021 Jan 14:S0092-8674(20)31681-0. doi: 10.1016/j.cell.2020.12.011. Online ahead of print. PMID: 33453153
The microbiota shields the host against infections in a process known as colonization resistance. …As such, pharmaceutical sequestration of sulfide perturbs the microbiotas composition and promotes pathogen invasion. Together, this work revea …