Immunoglobulin A Targets a Unique Subset of the Microbiota in Inflammatory Bowel Disease
Cell Host Microbe. 2020 Dec 31:S1931-3128(20)30665-X. doi: 10.1016/j.chom.2020.12.003. Online ahead of print. PMID: 33385335
Patients treated with anti-TNF-alpha therapies exhibited dramatically altered microbiota-specific IgA responses compared with controls. Furthermore, increased IgA coating of Oscillospira was associated with a delay in time to surgery. These results demonstrate that investi …
