Cytokine-specific autoantibodies shape the gut microbiome in autoimmune polyendocrine syndrome type 1

Petersen AØ, Jokinen M, Plichta DR, Liebisch G, Gronwald W, Oefner PJ, Vlamakis H, Chung DC, Ranki A, Xavier RJ.
J Allergy Clin Immunol. 2021 Apr 2:S0091-6749(21)00547-9. doi: 10.1016/j.jaci.2021.03.025. Online ahead of print. PMID: 33819509
OBJECTIVE: We aimed to understand the role of the gut microbiome in APS-1 symptoms and potentially alleviate common gastrointestinal symptoms by probiotic intervention. …Autoantibodies against cytokines appear to shape the gut microb