Curbing gastrointestinal infections by defensin fragment modifications without harming commensal microbiota
Commun Biol. 2021 Jan 8;4(1):47. doi: 10.1038/s42003-020-01582-0. PMID: 33420317
In mouse models, Pam-3 selectively reduced acute intestinal Salmonella and established Citrobacter infections, without compromising the core microbiota, hence displaying an added benefit to traditional broad-spectrum antibiotics. In conclusion, our data support the develop …
