Crossing the barriers: Revisiting the gut feeling in rheumatoid arthritis

Brandl C, Bucci L, Schett G, Zaiss MM.
Eur J Immunol. 2021 Feb 16. doi: 10.1002/eji.202048876. Online ahead of print. PMID: 33594693 Review.
Certain microbiota or their metabolites can cause a break in homeostasis by affecting the intestinal barrier integrity and permeability. However, an intact intestinal barrier is essential to separate the intestinal epithelium from toxins, microorganisms and antigens …