Comparison between 16S rRNA and shotgun sequencing data for the taxonomic characterization of the gut microbiota

Durazzi F, Sala C, Castellani G, Manfreda G, Remondini D, De Cesare A.
Sci Rep. 2021 Feb 4;11(1):3030. doi: 10.1038/s41598-021-82726-y. PMID: 33542369 Free PMC article.
In this paper we compared taxonomic results obtained by metataxonomics (16S rRNA gene sequencing) and metagenomics (whole shotgun metagenomic sequencing) to investigate their reliability for bacteria profiling, studying the chicken gut as a mode …