Giulia Colombo

A gut matter: the parallel aging of the microbiota and the brain

A gut matter: the parallel aging of the microbiota and the brain

MicrobiotaMi Comment 30_21
by Giulia Colombo

Age-related cognitive decline is associated with chronic low grade neuroinflammation that may result from a complex interplay among many factors, such as bidirectional communication between the central nervous system (CNS) and gut microbiota. This usually occurs through the immune, the neuroendocrine and the vagal pathways. Wu et al. compared 2-month-old (young) and 15-month-old (aged) mice to explore …

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Ecology of the multi-kingdom human gut microbiota assembly: insights from preterm infants

Ecology of the multi-kingdom human gut microbiota assembly: insights from preterm infants

MicrobiotaMi Comment 24_21
by Giulia Colombo

The new-born human gut is like a desert island for the microbiota: in fact, it evolves predictably with pioneer species colonizing the gut after birth, followed by an ordered succession of microorganisms. This colonizing process can be studied in a privileged manner in preterm infants, as well as the potentially shaping influences of the environment, the host and interactions …

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