A gut matter: the parallel aging of the microbiota and the brain

MicrobiotaMi Comment 30_21
by Giulia Colombo

Age-related cognitive decline is associated with chronic low grade neuroinflammation that may result from a complex interplay among many factors, such as bidirectional communication between the central nervous system (CNS) and gut microbiota. This usually occurs through the immune, the neuroendocrine and the vagal pathways. Wu et al. compared 2-month-old (young) and 15-month-old (aged) mice to explore …

Ecology of the multi-kingdom human gut microbiota assembly: insights from preterm infants

MicrobiotaMi Comment 24_21
by Giulia Colombo

The new-born human gut is like a desert island for the microbiota: in fact, it evolves predictably with pioneer species colonizing the gut after birth, followed by an ordered succession of microorganisms. This colonizing process can be studied in a privileged manner in preterm infants, as well as the potentially shaping influences of the environment, the host and interactions …

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Kin to win: kin selection drives cooperation in the human gut microbiota

MicrobiotaMi Comment 17_21
by Giulia Colombo

The management of complex microbial communities is a very promising tool in many fields, from microbiome manipulation to sustainable food production and climate regulation. To successfully engineer …

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Gut feelings: how the microbiota influences the neuroanatomical substrates of social bonding in a sex-specific manner

MicrobiotaMi Comment 07_21
by  Giulia Colombo

Growing evidence shows a pivotal role for the gut microbiota on the brain development, which may impact on behavior, too. Effah et al.’s recent article deals with this topic: the authors studied the oxytocin receptor’s expression and distribution in …

The circadian rhythm and the microbiota-gut-brain axis: a recurrent appointment with the neighbours

MicrobiotaMi Comment 02_21
by  Giulia Colombo

Teichman et al.’s recent review deals with the interactions between the microbiota-gut-brain axis and circadian rhythmicity, a topic that reminds us how reductive it is to think about ourselves as lonely bodies: we are more similar to small-scale ecosystems, instead, for our microbiota partners…