Calorie restriction prevents age-related changes in the intestinal microbiota
Aging (Albany NY). 2021 Mar 10;13(5):6298-6329. doi: 10.18632/aging.202753. Epub 2021 Mar 10. PMID: 33744869
The effect of calorie restriction (CR) on the microbiome, fecal metabolome, and colon transcriptome of adult and old male mice was compared. Life-long CR increased microbial diversity and the Bacteroidetes/Firmicutes ratio and prevented the age–rela …