Entries by MicrobiotaMi

Gut Microbiota-Neuron-Treg Triangle

MicrobiotaMi Comment 25_21
by Benedetta Sposito

It is well known that the microbiota influences the development and skewing of the intestinal immune system. Among the multiplicity of innate and adaptive immune cells that colonize the intestine, regulatory T cells (Tregs) are critical for maintaining tissue homeostasis and tolerance to commensal bacteria. Previous reports have described the ability of specific commensals to induce differentiation of RORγ+ Tregs in the mouse colon. Interestingly, these microbial …