Antimicrobial Prophylaxis and Modifications of the Gut Microbiota in Children with Cancer

Bossù G, Di Sario R, Argentiero A, Esposito S.
Antibiotics (Basel). 2021 Feb 3;10(2):152. doi: 10.3390/antibiotics10020152. PMID: 33546312 Free article. Review.
In children with cancer, chemotherapy can produce cytotoxic effects, resulting in immunosuppression and an augmented risk of febrile neutropenia and bloodstream infections. This has led to widespread use of antibiotic prophylaxis which, combined with intensive chemotherapy …