An enriched biosignature of gut microbiota-dependent metabolites characterizes maternal plasma in a mouse model of fetal alcohol spectrum disorder

Virdee MS, Saini N, Kay CD, Neilson AP, Kwan STC, Helfrich KK, Mooney SM, Smith SM.
Sci Rep. 2021 Jan 8;11(1):248. doi: 10.1038/s41598-020-80093-8. PMID: 33420159
Hierarchical clustering by principal component analysis and Pearson’s correlation of maternal plasma (813 metabolites) both identified MDPs as significant predictors for PAE. …These MDPs are abundant in human plasma, where they influence physiology and disease. Their alt …